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Search Results for " kras inhibitor-14 "

4

Compounds

Cat No. Product Name Synonyms Targets
T63235 KRAS inhibitor-14
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to...
T11768 KRAS G12C inhibitor 14 Ras
KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].
T62228 KRAS G12D inhibitor 14 Ras
KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM). KRAS G12D inhibitor 14 inhibits the active form of KRAS G12D (KRAS G12D-GTP), but not KRAS G13D.
T63887 SOS1-IN-14
SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutate...
TargetMol